MR (TOP300)
ID : Ahg478789
| Gene coexpression | ||
|---|---|---|
| MR | Locus | A.thaliana Description |
| 6 | Ahg473739 | |
| 6.32456 | Ahg480742 | AAA-type ATPase family protein |
| 6.48074 | Ahg325922 | pescadillo-related |
| 7.14143 | Ahg353700 | DNA topoisomerase, type IA, core |
| 12.2474 | Ahg933903 | heat shock protein 60-2 |
| 12.9615 | Ahg924591 | GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase, putative |
| 13.4164 | Ahg483090 | Transducin/WD40 repeat-like superfamily protein |
| 13.7113 | Ahg480455 | AAA-type ATPase family protein |
| 15.2315 | Ahg489491 | Glutamyl/glutaminyl-tRNA synthetase, class Ic |
| 18.7083 | Ahg943614 | Peptidase family M48 family protein |
| 20.9284 | Ahg483128 | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| 21.5639 | Ahg490127 | transducin family protein / WD-40 repeat family protein |
| 22.0227 | Ahg474241 | transferases;tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferases |
| 22.5832 | Ahg491312 | Pyridoxal phosphate (PLP)-dependent transferases superfamily protein |
| 23.1084 | Ahg950166 | co-factor for nitrate, reductase and xanthine dehydrogenase 5 |
| 23.2164 | Ahg470361 | prohibitin 2 |
| 23.8118 | Ahg937058 | |
| 23.9792 | Ahg315447 | ILITYHIA |
| 24.0832 | Ahg485156 | L-galactono-1,4-lactone dehydrogenase |
| 24.7386 | Ahg473719 | |
| 24.8596 | Ahg483524 | Ribosomal protein L2 family |
| 26.7395 | Ahg930498 | heat shock protein 60 |
| 27.9285 | Ahg485637 | RNA-binding (RRM/RBD/RNP motifs) family protein |
| 29.9165 | Ahg935767 | Transducin/WD40 repeat-like superfamily protein |
| 30 | Ahg480484 | tRNA/rRNA methyltransferase (SpoU) family protein |
| 30.7409 | Ahg480759 | RNA-binding (RRM/RBD/RNP motifs) family protein |
| 32.9848 | Ahg472969 | U2 snRNP auxiliary factor small subunit, putative |
| 34.176 | Ahg491623 | Class II aminoacyl-tRNA and biotin synthetases superfamily protein |
| 35.6371 | Ahg485913 | PDI-like 1-3 |
| 35.7771 | Ahg483634 | Translation elongation factor EFG/EF2 protein |
| 37.229 | Ahg497146 | Endomembrane protein 70 protein family |
| 37.9868 | Ahg930346 | L-Aspartase-like family protein |
| 38.833 | Ahg475389 | FAD/NAD(P)-binding oxidoreductase family protein |
| 40.1746 | Ahg482461 | Trimeric LpxA-like enzyme |
| 40.8167 | Ahg473448 | plastid developmental protein DAG, putative |
| 41.5331 | Ahg948747 | Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain |
| 41.5812 | Ahg472757 | Cobalamin biosynthesis CobW-like protein |
| 41.6893 | Ahg938089 | tetratricopeptide repeat (TPR)-containing protein |
| 42.0476 | Ahg327675 | pentatricopeptide (PPR) repeat-containing protein |
| 44.3621 | Ahg489563 | eukaryotic translation initiation factor 3B-2 |
| 44.4972 | Ahg479746 | putative mitochondrial RNA helicase 2 |
| 45.1664 | Ahg473651 | APR-like 4 |
| 45.4313 | Ahg491238 | SWIB/MDM2 domain superfamily protein |
| 45.8912 | Ahg483366 | Ribosomal protein L1p/L10e family |
| 46.2493 | Ahg951336 | cyclin dependent kinase group C2 |
| 46.7333 | Ahg903252 | FtsH extracellular protease family |
| 47.1699 | Ahg488863 | staurosporin and temperature sensitive 3-like A |
| 47.1805 | Ahg481268 | DNA/RNA polymerases superfamily protein |
| 48.1664 | Ahg496832 | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| 49.1935 | Ahg314794 | Domain of unknown function (DUF2431) |
| 49.3052 | Ahg484880 | histone deacetylase 3 |
| 49.9199 | Ahg471136 | SKP1-like 18 |
| 51.3323 | Ahg930461 | FAD/NAD(P)-binding oxidoreductase family protein |
| 51.9615 | Ahg909999 | GTP binding Elongation factor Tu family protein |
| 52.7447 | Ahg486983 | Mitochondrial glycoprotein family protein |
| 54.2586 | Ahg891118 | Endomembrane protein 70 protein family |
| 54.7449 | Ahg475311 | DEA(D/H)-box RNA helicase family protein |
| 55.5878 | Ahg942264 | Threonyl-tRNA synthetase |
| 55.7853 | Ahg937391 | translocon at the outer envelope membrane of chloroplasts 75-III |
| 56.6569 | Ahg952522 | RNAse l inhibitor protein 1 |
| 57.7581 | Ahg489809 | calcium-dependent protein kinase 4 |
| 58.6856 | Ahg485806 | fructokinase-like 1 |
| 58.9406 | Ahg485561 | 5'-3' exonuclease family protein |
| 59.7662 | Ahg340454 | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| 60 | Ahg325654 | transducin family protein / WD-40 repeat family protein |
| 60.0833 | Ahg924144 | Ribosomal protein S5/Elongation factor G/III/V family protein |
| 61.1882 | Ahg892406 | DEA(D/H)-box RNA helicase family protein |
| 61.4492 | Ahg480092 | Metallo-hydrolase/oxidoreductase superfamily protein |
| 61.5792 | Ahg321477 | phosphoribosylaminoimidazole carboxylase, putative / AIR carboxylase, putative |
| 61.7738 | Ahg904629 | pumilio 24 |
| 62.1611 | Ahg493903 | prohibitin 3 |
| 63.8514 | Ahg910344 | NOL1/NOP2/sun family protein |
| 65.4981 | Ahg336171 | toprim domain-containing protein |
| 65.7267 | Ahg486432 | |
| 65.8939 | Ahg474400 | histone H2A protein 9 |
| 67.1044 | Ahg922520 | staurosporin and temperature sensitive 3-like b |
| 67.1565 | Ahg896503 | RNA-binding (RRM/RBD/RNP motifs) family protein with retrovirus zinc finger-like domain |
| 69.5701 | Ahg318005 | protein arginine methyltransferase 3 |
| 70.3491 | Ahg473392 | early-responsive to dehydration stress protein (ERD4) |
| 70.4557 | Ahg487703 | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| 70.8237 | Ahg926563 | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| 72.8835 | Ahg493135 | O-fucosyltransferase family protein |
| 73.6682 | Ahg491917 | prohibitin 1 |
| 76.0263 | Ahg493295 | pleiotropic regulatory locus 1 |
| 76.6029 | Ahg943587 | Ribosomal RNA processing Brix domain protein |
| 78.2049 | Ahg480824 | metaxin-related |
| 78.2879 | Ahg936093 | signal peptide peptidase |
| 78.4857 | Ahg329212 | hydroxyproline-rich glycoprotein family protein |
| 78.867 | Ahg486562 | dihydrodipicolinate synthase 1 |
| 79.3221 | Ahg319609 | zinc ion binding |
| 79.5927 | Ahg495739 | TCP-1/cpn60 chaperonin family protein |
| 79.8749 | Ahg919093 | eukaryotic translation initiation factor 2 gamma subunit |
| 80 | Ahg476938 | Ribosomal protein S13/S18 family |
| 80.3119 | Ahg317013 | Ribosome recycling factor |
| 82.1462 | Ahg489362 | Sas10/Utp3/C1D family |
| 83.0422 | Ahg474002 | receptor for activated C kinase 1B |
| 84.4097 | Ahg934407 | RNA-binding (RRM/RBD/RNP motifs) family protein |
| 84.7231 | Ahg941463 | E1 C-terminal related 1 |
| 84.8528 | Ahg490266 | GTP binding Elongation factor Tu family protein |
| 85.3464 | Ahg934985 | Heat shock protein DnaJ with tetratricopeptide repeat |
| 85.5862 | Ahg471898 | KU70 homolog |
| 86.0814 | Ahg494737 | Zinc finger C-x8-C-x5-C-x3-H type family protein |
| 86.2322 | Ahg473787 | sequence-specific DNA binding transcription factors |
| 87.1091 | Ahg491627 | DDB1-CUL4 associated factor 1 |
| 90.1998 | Ahg924637 | DEA(D/H)-box RNA helicase family protein |
| 90.4212 | Ahg475877 | beta-ketoacyl reductase 1 |
| 91.2305 | Ahg928820 | Outer membrane OMP85 family protein |
| 93.1611 | Ahg478403 | DNA GYRASE A |
| 93.1665 | Ahg471752 | Tetratricopeptide repeat (TPR)-like superfamily protein |
| 93.2738 | Ahg485282 | Pentatricopeptide repeat (PPR) superfamily protein |
| 93.4666 | Ahg495431 | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| 93.5414 | Ahg933722 | S-adenosyl-L-methionine-dependent methyltransferases superfamily protein |
| 94.0479 | Ahg482032 | elongation factor family protein |
| 94.3716 | Ahg471887 | mitochondrial 28S ribosomal protein S29-related |
| 96.5609 | Ahg478793 | Ribosomal protein L34 |
| 97.3961 | Ahg486447 | LETM1-like protein |
| 98.1784 | Ahg894546 | S-adenosyl-L-methionine-dependent methyltransferases superfamily protein |
| 98.9242 | Ahg484088 | Ribophorin I |
| 98.9899 | Ahg474659 | Haloacid dehalogenase-like hydrolase (HAD) superfamily protein |
| 100.399 | Ahg492773 | |
| 100.737 | Ahg950414 | 60S acidic ribosomal protein family |
| 101.02 | Ahg358545 | RNA-metabolising metallo-beta-lactamase family protein |
| 102.103 | Ahg471010 | calreticulin 1b |
| 102.333 | Ahg484305 | Chaperone protein htpG family protein |
| 102.528 | Ahg489715 | phosphotyrosyl phosphatase activator (PTPA) family protein |
| 102.635 | Ahg478926 | cobalt ion binding |
| 103.286 | Ahg474779 | zinc finger (Ran-binding) family protein |
| 103.803 | Ahg478089 | Transcription factor jumonji (jmjC) domain-containing protein |
| 105.399 | Ahg920734 | Transducin/WD40 repeat-like superfamily protein |
| 105.613 | Ahg480033 | rotamase FKBP 1 |
| 105.83 | Ahg927376 | FTSH protease 12 |
| 106.184 | Ahg488471 | HEAT repeat-containing protein |
| 106.226 | Ahg470436 | AUX/IAA transcriptional regulator family protein |
| 106.658 | Ahg492356 | 26S proteasome, regulatory subunit Rpn7;Proteasome component (PCI) domain |
| 106.953 | Ahg496269 | Ribosomal protein S19e family protein |
| 107.098 | Ahg945645 | Clathrin adaptor complexes medium subunit family protein |
| 109.995 | Ahg486601 | DEA(D/H)-box RNA helicase family protein |
| 110.72 | Ahg490823 | mitochondrial heat shock protein 70-1 |
| 110.905 | Ahg942753 | RH39 |
| 110.973 | Ahg938805 | ARM repeat superfamily protein |
| 111.364 | Ahg486246 | Domain of unknown function (DUF1726) ;Putative ATPase (DUF699) |
| 112.103 | Ahg929045 | Tetratricopeptide repeat (TPR)-like superfamily protein |
| 113.591 | Ahg492124 | Co-chaperone GrpE family protein |
| 114.237 | Ahg915411 | DNA-binding bromodomain-containing protein |
| 114.878 | Ahg492065 | Met-10+ like family protein |
| 115.109 | Ahg935477 | methionine aminopeptidase 1A |
| 115.412 | Ahg487191 | DNA GYRASE B2 |
| 115.456 | Ahg895780 | zinc finger (MYND type) family protein / programmed cell death 2 C-terminal domain-containing protein |
| 115.568 | Ahg487529 | Ribosomal protein S4 (RPS4A) family protein |
| 116.833 | Ahg919332 | Rho termination factor |
| 116.833 | Ahg938716 | Protein of unknown function (DUF288) |
| 117.124 | Ahg482562 | RNA helicase family protein |
| 118.212 | Ahg489891 | Nascent polypeptide-associated complex (NAC), alpha subunit family protein |
| 118.381 | Ahg482051 | Tetratricopeptide repeat (TPR)-like superfamily protein |
| 119.063 | Ahg924663 | Zinc finger, C3HC4 type (RING finger) family protein |
| 119.105 | Ahg484871 | cyclophilin71 |
| 119.771 | Ahg496421 | Protein of unknown function (DUF3223) |
| 119.85 | Ahg480524 | nucleosome assembly protein 1;2 |
| 120.665 | Ahg481943 | Pseudouridine synthase family protein |
| 121.388 | Ahg913642 | |
| 121.491 | Ahg476456 | |
| 122.597 | Ahg488464 | Peptidyl-tRNA hydrolase family protein |
| 122.67 | Ahg934372 | Tetratricopeptide repeat (TPR)-like superfamily protein |
| 122.963 | Ahg471749 | Tetratricopeptide repeat (TPR)-like superfamily protein |
| 123.693 | Ahg929879 | |
| 125.02 | Ahg939120 | Ribosomal protein S13/S15 |
| 125.583 | Ahg485557 | ARM repeat superfamily protein |
| 125.638 | Ahg921780 | |
| 126.554 | Ahg937661 | Nucleic acid-binding, OB-fold-like protein |
| 126.807 | Ahg478805 | Kinase-related protein of unknown function (DUF1296) |
| 127.902 | Ahg323263 | ribosomal protein S15A D |
| 127.937 | Ahg950998 | Ribosomal protein S10p/S20e family protein |
| 128.18 | Ahg935789 | transducin family protein / WD-40 repeat family protein |
| 128.569 | Ahg890991 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein |
| 128.891 | Ahg920318 | ARM repeat superfamily protein |
| 129.012 | Ahg937676 | Ribosomal protein S5 domain 2-like superfamily protein |
| 129.093 | Ahg494787 | Chaperone DnaJ-domain superfamily protein |
| 129.263 | Ahg920383 | DYNAMIN-like 1C |
| 129.692 | Ahg475246 | DNA-directed RNA polymerase family protein |
| 129.73 | Ahg930508 | dehydratase family |
| 130.422 | Ahg937992 | Pentatricopeptide repeat (PPR) superfamily protein |
| 132 | Ahg478791 | Root hair defective 3 GTP-binding protein (RHD3) |
| 133.368 | Ahg929064 | RNA-binding KH domain-containing protein |
| 133.492 | Ahg940852 | nascent polypeptide-associated complex subunit alpha-like protein 3 |
| 134.666 | Ahg938748 | lysophosphatidyl acyltransferase 2 |
| 134.7 | Ahg495266 | Transducin/WD40 repeat-like superfamily protein |
| 134.759 | Ahg492170 | COP9 signalosome subunit 6B |
| 135.1 | Ahg473896 | MATE efflux family protein |
| 138.564 | Ahg480841 | Transducin/WD40 repeat-like superfamily protein |
| 139.032 | Ahg339621 | Mitochondrial substrate carrier family protein |
| 139.971 | Ahg490654 | FMN-linked oxidoreductases superfamily protein |
| 140.029 | Ahg493117 | tRNA/rRNA methyltransferase (SpoU) family protein |
| 140.499 | Ahg488841 | transferases;nucleotidyltransferases |
| 140.776 | Ahg920156 | Transducin/WD40 repeat-like superfamily protein |
| 141.351 | Ahg311691 | glyoxalase 2-4 |
| 141.986 | Ahg939309 | RING/U-box superfamily protein |
| 143.499 | Ahg928461 | HEAT SHOCK PROTEIN 89.1 |
| 143.823 | Ahg470642 | Ribosomal protein S5/Elongation factor G/III/V family protein |
| 144.049 | Ahg489519 | lon protease 1 |
| 144.43 | Ahg933494 | Pleckstrin homology (PH) domain superfamily protein |
| 144.634 | Ahg485276 | Transducin/WD40 repeat-like superfamily protein |
| 144.831 | Ahg929762 | Translation elongation factor EF1B/ribosomal protein S6 family protein |
| 144.831 | Ahg927888 | cysteine synthase 26 |
| 144.872 | Ahg473889 | succinate dehydrogenase 5 |
| 146.113 | Ahg478557 | Aha1 domain-containing protein |
| 146.144 | Ahg480760 | Tetratricopeptide repeat (TPR)-like superfamily protein |
| 148.54 | Ahg480227 | RNA helicase, ATP-dependent, SK12/DOB1 protein |
| 149.88 | Ahg331225 | ARM repeat superfamily protein |
| 150.659 | Ahg475230 | Glycine cleavage T-protein family |
| 151.109 | Ahg477850 | ribosomal protein L18 |
| 151.38 | Ahg476512 | transducin family protein / WD-40 repeat family protein |
| 153.232 | Ahg473029 | DNAJ heat shock family protein |
| 153.401 | Ahg926477 | WHIRLY 2 |
| 154.052 | Ahg476044 | fructokinase-like 2 |
| 154.159 | Ahg921968 | Transducin/WD40 repeat-like superfamily protein |
| 154.784 | Ahg483494 | Transducin/WD40 repeat-like superfamily protein |
| 154.919 | Ahg926900 | flavodoxin family protein / radical SAM domain-containing protein |
| 155.132 | Ahg486142 | embryo sac development arrest 7 |
| 155.422 | Ahg479744 | putative mitochondrial RNA helicase 1 |
| 155.885 | Ahg496221 | Anion-transporting ATPase |
| 156.01 | Ahg945614 | arginosuccinate synthase family |
| 156.058 | Ahg479224 | ribosomal protein L3 plastid |
| 156.192 | Ahg479874 | Ribosomal RNA processing Brix domain protein |
| 156.92 | Ahg919580 | Ribosomal protein L1p/L10e family |
| 157.683 | Ahg495837 | |
| 157.778 | Ahg919727 | Translation protein SH3-like family protein |
| 158.127 | Ahg482091 | ARM repeat superfamily protein |
| 158.625 | Ahg488797 | GPI transamidase component family protein / Gaa1-like family protein |
| 158.792 | Ahg489246 | cleavage and polyadenylation specificity factor 100 |
| 159.085 | Ahg475225 | cleavage and polyadenylation specificity factor 73-I |
| 160.025 | Ahg477335 | Ribosomal protein L13 family protein |
| 160.047 | Ahg487072 | Ribosomal protein S12/S23 family protein |
| 160.922 | Ahg490263 | Mitochondrial transcription termination factor family protein |
| 162.268 | Ahg487959 | overexpressor of cationic peroxidase 3 |
| 162.923 | Ahg482042 | Peptidase S24/S26A/S26B/S26C family protein |
| 163.518 | Ahg329184 | MA3 domain-containing protein |
| 165.245 | Ahg479277 | Surfeit locus 1 cytochrome c oxidase biogenesis protein |
| 167.218 | Ahg945188 | Nucleic acid-binding, OB-fold-like protein |
| 167.481 | Ahg924712 | LSD1-like 1 |
| 168.692 | Ahg920821 | NAP1-related protein 2 |
| 169.926 | Ahg941900 | ribosomal protein S11-beta |
| 170.526 | Ahg938043 | metallopeptidase M24 family protein |
| 171.831 | Ahg474386 | Peptidase S24/S26A/S26B/S26C family protein |
| 171.988 | Ahg920476 | Cobalamin biosynthesis CobW-like protein |
| 173.436 | Ahg470457 | Nucleolar GTP-binding protein |
| 173.62 | Ahg477605 | ribosomal protein S2 |
| 173.989 | Ahg474040 | C3HC zinc finger-like |
| 174.562 | Ahg495010 | prefoldin 3 |
| 174.929 | Ahg943763 | |
| 177.088 | Ahg920538 | Aldolase-type TIM barrel family protein |
| 177.485 | Ahg906386 | oxidoreductases, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;copper ion binding |
| 177.876 | Ahg934198 | |
| 179.287 | Ahg493833 | RNA binding Plectin/S10 domain-containing protein |
| 180.513 | Ahg930707 | bacterial hemolysin-related |
| 180.524 | Ahg316620 | hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides;ATP-dependent helicases;nucleic acid binding;ATP binding;RNA binding;helicases |
| 180.649 | Ahg493615 | Ribosomal protein S3 family protein |
| 181.841 | Ahg475487 | Ribosomal protein S5 family protein |
| 182.165 | Ahg355491 | Mog1/PsbP/DUF1795-like photosystem II reaction center PsbP family protein |
| 183.076 | Ahg487419 | splicing factor-related |
| 183.208 | Ahg477959 | ARM repeat superfamily protein |
| 183.804 | Ahg476796 | Ribophorin I |
| 184.348 | Ahg930087 | RNA methyltransferase family protein |
| 186.167 | Ahg481245 | Metal-dependent phosphohydrolase |
| 186.748 | Ahg944293 | Pentatricopeptide repeat (PPR) superfamily protein |
| 186.901 | Ahg473107 | Apoptosis inhibitory protein 5 (API5) |
| 187.371 | Ahg479267 | Molecular chaperone Hsp40/DnaJ family protein |
| 188.722 | Ahg480467 | RNA-binding CRS1 / YhbY (CRM) domain-containing protein |
| 189.087 | Ahg492111 | HIS HF |
| 189.315 | Ahg470426 | Ribosomal protein L14p/L23e family protein |
| 189.341 | Ahg349656 | histone deacetylase 2C |
| 190.512 | Ahg951569 | dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein |
| 191.499 | Ahg478776 | transmembrane nine 7 |
| 193.37 | Ahg940818 | peptidase M1 family protein |
| 193.688 | Ahg920943 | Regulator of chromosome condensation (RCC1) family protein |
| 194.422 | Ahg491725 | Integral membrane Yip1 family protein |
| 194.648 | Ahg470511 | NAD(P)-binding Rossmann-fold superfamily protein |
| 194.666 | Ahg926472 | Pentatricopeptide repeat (PPR) superfamily protein |
| 194.838 | Ahg334100 | lactoylglutathione lyase family protein / glyoxalase I family protein |
| 195.632 | Ahg924525 | 6-phosphogluconate dehydrogenase family protein |
| 195.653 | Ahg478024 | GTP-binding family protein |
| 195.752 | Ahg478388 | Transducin/WD40 repeat-like superfamily protein |
| 196.627 | Ahg896391 | TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein |
| 197.109 | Ahg478722 | |
| 197.307 | Ahg495317 | fibrillarin 1 |
| 197.719 | Ahg485780 | Ribosomal protein S3 family protein |
| 197.909 | Ahg474319 | Insulinase (Peptidase family M16) protein |
| 198.167 | Ahg489792 | Nucleoside diphosphate kinase family protein |
| 198.338 | Ahg477224 | PENTATRICOPEPTIDE REPEAT 596 |
| 198.997 | Ahg484564 | carbamoyl phosphate synthetase A |
| 199.715 | Ahg492441 | Chaperone protein htpG family protein |
| 201.047 | Ahg476916 | PDI-like 1-2 |
| 201.06 | Ahg920450 | periodic tryptophan protein 2 |
| 201.395 | Ahg471063 | Translation elongation factor EF1B, gamma chain |
| 201.633 | Ahg492089 | PDI-like 5-4 |
| 201.693 | Ahg939125 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein |
| 202.114 | Ahg486421 | Ribosomal L38e protein family |
| 202.786 | Ahg920787 | Ribosomal protein L6 family protein |
| 202.938 | Ahg496347 | calnexin 1 |
| 202.99 | Ahg313639 | nuclear RNA polymerase A2 |
| 203.162 | Ahg894080 | RNA cyclase family protein |